Discover Validate Design
Integrating biophysics, enzymology, and structure-based drug design
Discover Validate Design
Integrating biophysics, enzymology, and structure-based drug design
Innovative Solutions for Drug Discovery
Hit Identification
Hit Identification
Hit ID begins with a clear, focused screening strategy that is appropriate for the target.
- Screening Strategy and Development
- CRO Management
- Data Analysis
- Druggability Assessment
Hit Validation
Hit Identification
We help clients prioritize screening hits so that chemistry efforts can be focused on those with the highest likelihood of becoming leads.
- Biophysical Characterization
- Solubility Assessment
- Target-Ligand Engagement
- Mechanism of Action
Lead Optimization
Lead Optimization
Once leads have been identified, we help optimize them through structural and biophysical methods
- Structure-Based Drug Design (X-ray, Cryo-EM)
- Biophysical Analysis (SPR, ITC, TSA, BLI, Mass Photometry)